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API INTERMEDIATES & PRECURSORS

S.NO CHEMICAL NAME SR CAS NO Application
1 Burgess reagent R 629-648-8 Nirmatrelvir and Telaprevir APIs and Dehydrating agent
2 Pyridine 3 -Sulphonyl chloride -- 16133-25-8 --
3 (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride -- 188416-35-5 Voriconazole
4 (2R,3S/2S,3R)-2-(2,4-Difluorophenyl)-3-(5-fluoro-4-pyriMidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol (Racemic Voriconazole)L -- 188416-29-7 Voriconazole
5 4-Methyl-3-[4-(3-pyridyl)pyrimidin-2-ylamino]aniline -- 152460-10-1 Imatinib
6 2-Chloro-4-amino-6,7-dimethoxyquinazoline -- 23680-84-4 Alfuzosin, Prazosin, Terazosin, Zeftinib
7 2,5-dichloropyridine -- 22536-67-0 Macitentan
8 2-Chloro-5-bromopyridine -- 32779-36-5 Macitentan
9 5-(4-Bromophenyl)-4,6-dichloropyrimidine -- 146533-41-7 Macitentan
10 1-(Sulfamoylamino)Propane -- 147962-41-2 Macitentan
11 O-Benzylhydroxylamine Hydrochloride -- 2687-43-6 Finechemical
12 4-(4-aminophenyl) morpholin-3-one -- 3438056-69-0 Rivaroxaban
13 (S)-2-((2-Oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)isoindoline-1,3-dione -- 446292-08-6 Rivaroxaban
14 (S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one -- 446292-10-0 Rivaroxaban
15 (S)-2-((2-Oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)isoindoline-1,3-dione -- 446292-08-6 Rivaroxaban
16 2-anilinoethanol -- 122-98-5 Rivaroxaban
17 (S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline -- 118864-75-8 Solifenacin Succinate
18 1-Phenyl-3,4-dihydroisoquinoline -- 52250-50-7 Solifenacin Succinate
19 2-Butynoic acid (Tetrolic acid) -- 590-93-2 Fine chemical
20 4-n-butylresorcinol R 18979-61-8 Cosmetic use
21 Pyridine-3-sulfonylchloride -- 16133-25-8 Vonoprazan
22 2-amino-5-nitrothiazole -- 121-66-4 Fine chemical
23 3,5-dihydroxy benzoic acid -- 99-10-5 --
24 4-BROMO PHENYL ACITIC ACID -- -- --
25 METHYL SALICYLATE -- -- --
26 SALICYLAMIDE -- -- --
27 2 ETHOXY BENZOIC ACID -- -- --
28 Pthalyl amlopdipine -- -- --
29 N-METHYL DESLORATADINE -- 38092-89-6 --
30 DIBENZOSUBERENONE -- 2222-33-5 --
31 DIBENZOSUBERONE -- 1210-35-1 --
32 N-METHYL-4-CHLOROPIPERIDINE -- 5570-77-4 --
33 N-METHYL-4-CHLOROPIPERIDINE HCL -- 5382-23-0 --
34 N-METHYL-4-PIPERIDONE -- 1445-73-4 --
35 N-ISOBUTYL-4-PIPERIDONE -- 72544-16-2 --
36 N-CARBETHOXY-4-PIPERIDONE -- 29976-53-2 --
37 N-METHYL-4-HYDROXY-PIPERIDINE -- -- --
38 10,10 dimethyl anthrone -- -- --
39 3-Bromo-1,3,4,5-tetrahydro-2H- -benzazepin-2-one. S 86499-96-9 BENAZEPRIL
40 tert-Butyl3S-amino-2,3,4,5-tetrahydro-1H-(l]benae pin-2-one-l-acetate tartrate. -- 117770-66-8 BENAZEPRIL
41 (S)-t-Butyl2-(3-amino-2-oxo-2,3,4,5-tetrahydro -1H-b enzo[b]azepin-1-yl)acetate. -- 109010-60-8 BENAZEPRIL
41 4-Bromophenyl acetic acid. -- 1878-68-8 BILASTINE HCI
42 (R)-4-Propyldihydrofuran-2(3H)-one. -- 63095-51-2 BRIVARACETAM
43 N-Methyl-3-phenylpiperazine(NM3PP). -- 5271-27-2 MIRTAZAPINE
44 1-(3-Carboxypyrid-2-yl)-2-phenyl-4-methyl-piperazine. -- 61338-13-4 MIRTAZAPINE.
45 1-(3-Hydroxymethylpyridin-2-yl)-4-methyl-2-phenyl piperazine -- 61337-89-1 MIRTAZAPINE
46 2-(Chloromethyl)-3,4-dimethoxypyridine hydrochloride -- 72830-09-2 PANTOPRAZOLE
47 5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole -- 97963-62-7 PANTOPRAZOLE
48 2-(Chloromethyl)-4 -methoxy-3,5-dimethylpyridine hydrochloride -- 86604-75-3 OMEPRAZOLE
49 2-Mercapto-5-methoxybenzimidazole. -- 37052-78-1 OMEPRAZOLE
50 2,6-Dihydroxymethyl Pyridine(DHMP) -- 1195-59-1 SPECIALITY CHEMICAL
51 2,6-Bis(dichloromethyl)pyridine Hydrochloride (DCMP) -- 55422-79-2 SPECIALITY CHEMICAL
52 1-( 1-hydroxy-5 6,7,8-tetrahydronaphthalen-2-yl) ethanone. -- 95517-07-0 SPECIALITY CHEMICAL
53 2‐(Chloromethyl)‐4‐methylquinazoline V 109113‐72‐6 Linagliptin
54 8-Bromo-3-methyl-1H-purine-2,6(3H,7H)-dione -- 93703-24-3 Linagliptin
55 (R)‐3‐(Boc‐Amino)piperidine -- 309956‐78‐3 Linagliptin
56 (1R ,2R )‐1,2‐Cyclohexanedimethanol -- 65376‐05‐8 Lurasidone
57 ((1R,2R)-2-{[Methyl Sulphonyl]methyl}Cyclohexyl)Methyl methane sulfoate -- 66347-68-0 Lurasidone
58 (3aR ,4S ,7R ,7aS ) 4,7‐Methano‐1H ‐isoindole‐1,3(2H )‐dione -- 14805‐29‐9 Lurasidone
59 (R,R)‐1,2‐Bis(methanesulfonyloxymethyl)cyclohexane -- 186204‐35‐3 Lurasidone
60 3‐(4‐Chlorobutyl)‐1H ‐indole‐5‐carbonitrile -- 143612‐79‐7 Vilazodone
61 5‐Aminobenzofuran‐2‐carboxylic acid ethyl ester -- 174775‐48‐5 Vilazodone
62 Ethyl5‐(4‐tert‐butoxy‐carbonyl‐1‐piperizinyl)benzofuran‐2‐carboxilate -- 183288‐43‐9 Vilazodone
63 7‐chloro‐1H‐quinazolin‐4‐one -- 31374‐18‐2 Albaconazole
64 1‐[[(2R, 3S)‐2‐(2, 4‐Difluorophenyl)‐3‐methyloxiranyl] methyl]‐1H‐1, 2, 4‐ -- 127000‐90‐2 Efinaconazole
65 4‐methylene piperidine‐HCl -- 144230‐50‐2 Efinaconazole
66 1‐(((2R,3S)‐2‐(2,5‐difluorophenyl)‐3‐Methyloxiran‐2‐yl)Methyl)‐1H‐1,2,4‐triazole -- 241479‐73‐2 Isavuconazole
67 2-Bromo-4′-cyanoacetophenone -- 20099-89-2 Isavuconazole
68 1‐(((2R,3S)‐2‐(2,5‐difluorophenyl)‐3‐Methyloxiran‐2‐yl)Methyl)‐1H‐1,2,4‐triazole -- 241479‐73‐2 Isavuconazole
69 1‐(((2R,3S)‐2‐(2,5‐difluorophenyl)‐3‐Methyloxiran‐2‐yl)Methyl)‐1H‐1,2,4‐triazole -- 241479‐73‐2 Isavuconazole
70 2-Bromo-4′-cyanoacetophenone -- 20099-89-2 Isavuconazole
71 (2R,3R)‐3‐(2,5‐Difluorophenyl)‐3‐hydroxy‐2‐Methyl‐4‐(1H‐1,2,4‐triazol‐1‐yl) thiobutyramide Hydrate Hydrosulfate . (free base) -- 2368421‐58‐3 Isavuconazole
72 1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzol[d]imidazole -- 110963-63-8 Bilastine HCl
73 Methyl2-(4-(2-bromoethyl)phenyl)-2-methylpropanoate -- 1394117-23-7 Bilastine HCl
74 2-[4-(2-{4-[1(2-ethoxyethyl)-1H-1,3-benzodiazol-2-yl]piperidine-1- yl}ethyl)phenyl]-2-methylpropanoic acid -- 202189-78-4 Bilastine HCl
75 1-(3-Ethyl-4-(hydroxymethyl)phenyl)ethanone -- 1378888-43-7 Siponimod
76 3-Azetidinecarboxylic acid -- 36476-78-5 Siponimod
77 ethyl 7-bromo-2,2- dimethylheptanoate -- 123469-92-1 Bempedoic acid
78 2,2,14,14-tetramethyl-8-oxopentadecanedioic acid. -- 413624-71-2 Bempedoic acid
79 (2R"3R)-3-(3-methoxyphenyl)-N,N,2-trimethylpentan- 1-amine -- 175591-22-7 Tapentadol HCl
80 Methyl 4-(3,5-dichlorobenzamido)-3-hydroxybenzoate -- 1184581-58-5 Tafamidis Meglumine
81 2-(3,5-dichlorophenyl)benzo [d] oxazole-6-carboxylic acid -- 594839-88-0 Tafamidis Meglumine
82 1‐(((2R,3S)‐2‐(2,5‐difluorophenyl)‐3‐Methyloxiran‐2‐yl)Methyl)‐1H‐1,2,4‐triazole -- 241479‐73‐2 Isavuconazole
83 5-[2-[2-(2-Ethoxyphenoxy)ethylamino]propyl]-2-methoxy-benzenesulfonamide J 106133-20-4 Tamsulosin hydrochloride
84 2-(2-Ethoxyphenoxy)ethyl bromide -- 3259-03-8 Tamsulosin hydrochloride
85 5-Acetonyl-2-methoxybenzene sulfonamide -- 116091-63-5 Tamsulosin hydrochloride
86 2-(2-Ethoxyphenoxy)ethyl Methanesulfonate -- 169506-15-4 Tamsulosin hydrochloride
87 R-(-)-5-(2-Amino-propyl)-2-methoxy-benzenesulfonamide -- 112101-81-2 Tamsulosin hydrochloride
88 5-[®-(2-Aminopropyl)]-2-methoxybenzenesulfonamide hydrochloride -- 112101-75-4 Tamsulosin hydrochloride
89 3-Pyridylacetic acid hydrochloride -- 6419-36-9 Risedronate Sodium.
90 3-Pyridylacetic acid -- 501-81-5 Risedronate Sodium.
S.NO Chemical Name CAS Number Final product
1 4-Bromo phenyl Acetic Acid 1878-68-8 Bilastine
2 4-Bromo phenyl methyl Ester 3650-78-0 71205-17-9 Masitentan
3 OME Nitro compound -- Omeprazole Esomiprazole
4 Methyl nitrobenzoate - 4-butyrylamino-3-methyl-5- 152628-01-8 Telmisartan
5 2-propyl-4-methylbenzimidazole-6- carboxylic acid 152628-03-0 Telmisartan
6 2-n-Propyl-4-Methyl-6-(1-Methyl benzimidazole-2-yl) Benzimidazole 152628-02-9 Telmisartan
7 N-methyl-O- phenylenediaminedihydrochloride 25148-68-9 Telmisartan
8 -Bromomethyl-2-Cyanobiphenyl (Bromo OTBN) 114772-54-2 Telmisartan
9 Benzhydrol 91-01-0 Cinnarzine
10 1-Benzhydrol Piperazine 212-667-7 Cinnarzine
11 Para Chloro Benzophenone 134-85-0 Citrazine
12 Para Chloro Benzhydrol 119-56-2 Citrazine
13 Para Chloro Benzhydrol Piperazine 303-26-4 Citrazine
S.NO Chemical Name Structure CAS Number Intermediate for Commercial Batch Status
1 4-Amino-2-Chloro-6,7-Dimethoxy Quinazoline  23680-84-4 Alfuzosin/erazosin/ Doxazosin/ Prazosin(Anti Hyper) Commercialized at 150 Kg scale.
2 4-Amino-2-Chloro-6,7-Dimethoxy Quinazoline  23680-84-4
3 (1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline  118864-75-8 Solifenacin Succinate(Urine Infection) Commercialized at 300 Kg scale
4 1-Phenyl-1,2,3,4-tetrahydroisoquinoline  22990-19-8
5 (2R,3S/2S,3R)-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol  182230-43-9 Voriconazole Commercialized at 75Kg batch size
6 (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride  188416-35-5 Voriconazole
7 4,6-dichloro-2-propylthiopyrimidine-5-amine  145783-15-9 Intermediate Ticagrelor Lab trials completed, Jan for Commercial trials
8 (S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3 yl) phenyl)morpholin-3-one  446292-10-0 Rivaroxaban Anticoagulant medication Commercial at 10 Kg scale.No commercial as off now.
9 4-(4-Aminophenyl)morpholin-3-one  38056-69-0
10 2-[(S)-(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine (2R,3R)-2,3-Dihydroxybutanedioate  210095-58-2 Bipotastine Besilate Development at R&D is continuing.Expected for pilot trial Jan’21
11 Bepotastine Base  190786-43-7
12 5-Bromo-2-chloropyrimidine  32779-36-5 Intermediate Macitentan Pilot trials completed at 60Kg scale.
13 N-Propylsulfamide  147962-41-2
14 4,6-Dichloro-5-(4-bromophenyl)pyrimidine  146533-41-7
15 1-(3-Chloropropyl)-1,3-dihydrobenzimidazol-2-one -- 62780-89-6 -- Intermediate for Domperidone
16 4 methyl acetophenone -- 122-00-9 -- Multiple application pharma and agrochemicals
17 Methyl salicylate -- -- -- Pharma and other applications.
18 Salicylamide -- -- -- Pharma and other applications.
19 Salicylic Acid -- -- -- Pharma and other applications.
20 Salicylic acid esters -- -- -- Pharma and other applications.